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Updated: Jun 30, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
10:28

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers

Published on: September 20, 2018

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染色体修饰剂EP400 调节小鼠卵细胞质量和紫芽基因组激活

Qing Tian1,2, Ying Yin3,4,5, Yu Tian1

  • 1Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|March 17, 2024
PubMed
概括

孕产妇的Ep400对卵细胞质量和早期胚胎发育至关重要. 它的枯竭会损害胚胎基因组激活 (ZGA) 并导致发育停止,突出其在母体到胚胎过渡中的关键作用.

关键词:
EP400 EP400 EP400 EP400 EP400 EP400 EP400 EP400 EP400 EP400 EP400 EP400 EP400H3.3 其他类型卵子细胞 卵子细胞在植入前的植入前.紫毒基因组激活活动

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Analysis of Chromosome Segregation, Histone Acetylation, and Spindle Morphology in Horse Oocytes12:11

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