可定制或可分散的薄膜:喷墨打印和数据矩阵编码,用于个性化的皮剂量
Lucía Rodríguez-Pombo1, Paola Carou-Senra1, Erea Rodríguez-Martínez1
1Departamento de Farmacología, Farmacia y Tecnología Farmacéutica, I+D Farma (GI-1645), Facultad de Farmacia, Instituto de Materiales (iMATUS) and Health Research Institute of Santiago de Compostela (IDIS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
International journal of pharmaceutics
|March 17, 2024
概括
喷墨打印创建了个性化药物膜与数据矩阵,以获得更安全的药物. 这项技术提高了医疗保健中的药物输送和可访问性.
科学领域:
- 制药技术 制药技术 制药技术
- 药物输送系统 药物输送系统
- 数字健康数字健康
背景情况:
- 个性化医疗需要灵活而精确的药物剂量.
- 传统的药物配方方法可能无法满足个性化治疗的需求.
- 制造技术的创新对于推进医药护理至关重要.
研究的目的:
- 使用喷墨印刷技术开发含有药物的可溶性膜.
- 在电影上的数据矩阵模式中编码关键药物信息.
- 为医疗保健应用程序创建专门的数据矩阵生成器软件.
主要方法:
- 开发和描述含有皮 (HC) 的药用墨水.
- 研究提高HC可溶性的策略 (例如β-环氧,Soluplus®小粒,辅溶剂).
- 使用定制软件进行自动化数据矩阵生成和打印层识别.
主要成果:
- 成功制备灵活的,低剂量,含有药物的可溶性薄膜.
- 共同溶剂系统影响了药物的溶解性,油墨粘度和表面张力.
- β-环氧素复合改善了药物沉积,而基于微粒的油墨不适合印刷.
- 开发的软件有效地适应了数据矩阵大小和打印层.
结论:
- 喷墨印刷可以创建个性化的,信息编码的药物输送系统.
- 专用软件提高了个性化医疗的安全性和可访问性.
- 这种方法为量身定制的药物治疗提供了革命性的进展.
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