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Alicia Therese Dennis¹, Emily Traer², Hilmy Ismail³

¹Division of Obstetric Anesthesia, Department of Anesthesiology, Perioperative medicine and Pain Medicine, Brigham and Women's Hospital, Boston, MA; Department of Anaesthesia, The Royal Women's Hospital, Parkville, Australia; Department of Anaesthesia and Perioperative Medicine, Western Health, Sunshine, Australia; School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, Victoria, Australia; Departments of Critical Care, Obstetrics and Gynaecology, and Pharmacology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Australia; Honorary researcher, Peter MacCallum Cancer Centre, Victoria, Australia.

American heart journal

|March 17, 2024

概括

本研究建立了使用心肺运动测试 (CPET) 和增量穿步行测试 (ISWT) 的孕妇运动反应的参考间隔. 血红蛋白水平,而不是费里丁,与运动能力相关,这表明监测血红蛋白对母亲健康至关重要.

科学领域:

产科和妇科产科和妇科
心脏病学心脏病学
运动生理学运动生理学

背景情况:

怀孕期间的心血管疾病对全球健康构成重大风险.
运动测试可以评估心血管反应和分层妊娠风险.
建立氧气利用 (V·O₂) 和步行距离的参考间隔对于怀孕期间的运动处方至关重要.

研究的目的:

使用CPET确定V̇O₂在静止状态,无氧值 (AT) 和亚最大运动的参考间隔.
为了确定增量穿步行测试 (ISWT) 的参考间隔.
开发一个相关方程,从ISWT距离预测亚最大V̇O₂.
为了探索血红蛋白 (Hb) 和费里丁和V̇O₂在第二个三个月的AT之间的关系.

主要方法:

心肺运动测试 (CPET) 和增量穿步行测试 (ISWT) 在健康的孕妇 (第二个三个月) 中进行.
建立了V̇O₂和ISWT距离的参考间隔.
计算了ISWT距离和亚最大V̇O₂之间的相关性.
记录了血红蛋白和费里丁水平,并与AT的V̇O₂相关联.

主要成果:

对于V·O₂ (休息时间:2.9-5.3,AT:8.1-20.7,亚最大值:14.1-30.5毫升/千克/分钟) 和ISWT (218-1058米) 进行了参考间隔.
来自ISWT距离的亚最大V̇O₂的预测方程被开发出来 (V̇O₂ = 0.012*ISWT + 14.7).
在AT (r=0.2538,P=.016),血红蛋白度与V̇O₂正相关,而费里丁没有显示出线性关联.

结论:

CPET和ISWT对于评估孕妇的运动能力是安全和可行的.
确定的参考间隔和预测方程可以帮助临床实践和研究.
血红蛋白水平与运动能力有关,而不是费里丁,这凸显了监测和纠正怀孕期间低血红蛋白的重要性.

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