相关实验视频

Updated: Jun 30, 2025

Using Nanoplasmon-Enhanced Scattering and Low-Magnification Microscope Imaging to Quantify Tumor-Derived Exosomes

Using Nanoplasmon-Enhanced Scattering and Low-Magnification Microscope Imaging to Quantify Tumor-Derived Exosomes

Published on: May 24, 2019

乳腺癌衍生外体:治疗学观点和含义

Ram Mohan Ram Kumar¹, Rajan Logesh², Suresh Joghee²

¹Department of Pharmaceutical Biotechnology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India.

Clinica chimica acta; international journal of clinical chemistry

|March 17, 2024

概括

乳腺癌外基因组 (BCex) 是瘤进展和耐药性的关键参与者. 操纵这些细胞外囊泡为乳腺癌治疗提供了有前途的治疗和诊断途径.

科学领域:

在瘤学瘤学.
生物化学生物化学
分子生物学分子生物学

背景情况:

乳腺癌 (BC) 是全球女性的主要恶性瘤.
传统的BC治疗具有显著的副作用,需要新的方法.
细胞外囊泡 (EVs),特别是外体,在癌症进展和耐药性方面至关重要.

研究的目的:

对乳腺癌中外体细胞的治疗和诊断影响进行审查.
突出乳腺癌衍生异体 (BCex) 在疾病进展中的作用.
讨论基于外体的BC疗法的未来研究方向.

主要方法:

文献综述侧重于乳腺癌中的外体组研究.
对外体生物发生,功能和载荷的分析.
评估BCex在调节癌症特征和治疗耐药性的作用.

主要成果:

BCex通过调节细胞增殖,血管新生,转移和免疫逃避来影响BC进展.
外体体与对常规疗法的耐药性发展有关.
来自BC的外体细胞显示出在体液中作为非侵入性诊断生物标志物的潜力.

结论:

针对性地操纵BCex对乳腺癌具有显著的治疗潜力.
外体细胞对诊断和治疗乳腺癌都很有价值.
进一步的研究是必不可少的,以充分实现BC外体的临床应用.

关键词:

乳腺癌是什么? 乳腺癌是什么?诊断诊断诊断诊断诊断外基因组是外基因组的组成部分.细胞外囊泡中的细胞外囊泡.治疗疗法治疗疗法

更多相关视频

An Enrichment Method for Small Extracellular Vesicles Derived from Liver Cancer Tissue

An Enrichment Method for Small Extracellular Vesicles Derived from Liver Cancer Tissue

Published on: February 3, 2023

Isolation and Profiling of MicroRNA-containing Exosomes from Human Bile

Isolation and Profiling of MicroRNA-containing Exosomes from Human Bile

Published on: June 13, 2016

相关概念视频

Overview of Exosomes

Overview of Exosomes

Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...