相关实验视频

Updated: Jun 30, 2025

Protein Purification-free Method of Binding Affinity Determination by Microscale Thermophoresis
10:22

Protein Purification-free Method of Binding Affinity Determination by Microscale Thermophoresis

Published on: August 15, 2013

30.6K

系统的氨基酸分析:治疗性蛋白质的灭绝系数确定方面的进展

Ya Xu1, Zhenzhen Shao1, Lei Zhang1

  • 1Analytical Science Development, Henlius Biologics Co., Ltd, 5155 Guangfulin Road, Shanghai, 201616, China.

Analytical biochemistry
|March 17, 2024
PubMed
概括

精确的灭绝系数 (EC) 测量对于生物产品开发至关重要. 这项研究优化了氨基酸分析方法,显著提高了生物制品的EC确定精度和稳定性.

关键词:
氨基酸分析 氨基酸分析灭绝系数 灭绝系数蛋白质的数量 蛋白质的量治疗性蛋白质是一种治疗性蛋白质.

更多相关视频

Author Spotlight: Advancing Biotherapeutic Mass Calculation by Introducing mAbScale, a Python-Based Desktop Application04:24

Author Spotlight: Advancing Biotherapeutic Mass Calculation by Introducing mAbScale, a Python-Based Desktop Application

Published on: June 16, 2023

1.5K
Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry13:26

Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry

Published on: September 13, 2014

61.7K

相关概念视频

Protein-Drug Binding: Determination Methods01:22

Protein-Drug Binding: Determination Methods

Determining protein-drug binding can be achieved through indirect and direct methods, each providing valuable insights into the interaction between proteins and drugs.
Indirect methods involve isolating the bound drug from its free form in biological samples such as blood, serum, or plasma. These techniques aim to measure the percentage of drugs bound to proteins. Equilibrium dialysis is a commonly used method where the free drug concentration at equilibrium is measured by separating the bound...
179
The Equilibrium Binding Constant and Binding Strength02:18

The Equilibrium Binding Constant and Binding Strength

The equilibrium binding constant (Kb) quantifies the strength of a protein-ligand interaction. Kb can be calculated as follows when the reaction is at equilibrium:
12.9K