神经内分泌瘤的神经神经瘤神经瘤的神经神经系统表现
Marco Zoccarato1, Wolfgang Grisold2
1Neurology Unit O.S.A., Azienda Ospedale-Università di Padova, Padova, Italy.
Handbook of clinical neurology
|March 17, 2024
概括
神经内分泌瘤 (NENs) 很少会通过瘤综合征或激素产生影响神经系统. 这些罕见的神经系统并发症与瘤预后和内分泌影响一起影响患者的结果.
科学领域:
- 在瘤学瘤学.
- 神经学 神经学
- 内分泌学 在内分泌学.
背景情况:
- 神经内分泌瘤 (NENs) 是源自神经内分泌细胞的多种瘤,最近的分类更新是在世卫组织第5版中.
- NEN很少涉及中枢或外围神经系统,主要是通过瘤综合征或内分泌影响.
研究的目的:
- 探索神经系统参与NENs的机制和表现.
- 突出介质瘤综合征在NENs中的作用.
- 讨论神经和内分泌效应对患者结果的影响.
主要方法:
- 对NENs和神经系统并发症的现有文献的审查.
- 分析导致瘤综合征的免疫和内分泌机制.
- 瘤特征与神经和内分泌表现的相关性.
主要成果:
- 麻性神经系统综合征 (PNS) 是免疫介导的,在NEN中很少见,除了梅克尔细胞癌和小细胞肺癌.
- 内分泌表现在NEN中很常见,并可能导致神经系统症状.
- 患者的结果受到瘤预后,神经复发症和内分泌影响的显著影响.
结论:
- 了解神经系统参与NEN的机制和临床范围对于全面的患者管理至关重要.
- 考虑瘤特征,神经系统并发症和内分泌作用的综合方法对于改善NEN患者的治疗结果至关重要.
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