在中国成年人中准脊椎肌肉大小和骨髓炎的参考值,全国多中心研究
Wenkai Wu1, Fangfang Duan2, Kai Li3
1Department of Spine Surgery, Beijing Jishuitan Hospital, National Centre for Orthopaedics, Capital Medical University, Beijing, China; JST sarcopenia Research Centre, National Centre for Orthopaedics, Beijing Research Institute of Traumatology and Orthopaedics, Beijing Jishuitan Hospital, Beijing, China.
Academic radiology
|March 17, 2024
概括
副脊椎肌肉随着年龄的增长而减小,并增加脂肪. 这项研究为中国成年人建立了与年龄相关的参考值,揭示了更年期妇女和老年男性的加速肌肉损失.
科学领域:
- 老年学是一门学科.
- 肌肉骨健康 肌肉骨健康
- 放射学 放射学是一门学科.
背景情况:
- 准脊椎肌肉经历了与年龄相关的显著变化,包括体型减小和脂肪透.
- 缺少与年龄相关的准脊椎肌肉参数变化的确定的参考值.
- 了解这些变化对于评估老年人群中脊柱健康至关重要.
研究的目的:
- 在中国成年人群中确定准脊椎肌肉参数的特定年龄和性别的参考值.
- 量化肌肉面积,密度和脂肪分数与年龄相关的变化.
- 为了确定经历加速肌肉损失的特定年龄组.
主要方法:
- 使用来自中国脊椎和部行动 (CASH) 队列的基线数据进行横截面研究.
- 招募了4305名21至80岁的中国社区成年人.
- 定量计算断层扫描 (QCT) 测量了L3/L5的psoas和副脊髓肌肉;使用LMS方法构建的与年龄相关的参考值.
主要成果:
- 准脊椎肌肉的肌肉面积和密度与年龄相关的下降,脂肪分数增加.
- 肌肉截面面积每年减少 -0.47% (psoas) 和 -0.53% (脊柱) 在男性,和 -0.19% (psoas) 和 -0.23% (脊柱) 在女性 (年龄25-75).
- 更年期/更年期后妇女 (45-75岁) 和中年/老年男性 (35-55岁,60-75岁) 间歇性地出现加速肌肉损失,L5的变化比L3更明显.
结论:
- 在更年期/更年期后妇女和中年/老年男性中发现了加速椎肌肉损失的明显模式.
- 这些发现为了解与年龄相关的准脊椎肌肉变化和骨髓变提供了重要的参考值.
- 这些结果有助于未来对老年人群中肉症和相关脊柱疾病的研究.
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