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Updated: Jun 30, 2025

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing
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通过高产量联结和多重丰富测序来增强新型低频基因融合的检测

Yi Wu1, Jinxiao Guo2, Wenjun Li3

  • 1School of Biomedical Engineering, Zhangjiang Institute for Advanced Study and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai, 200240, China.

Angewandte Chemie (International ed. in English)
|March 17, 2024
PubMed
概括

这项研究引入了一种用于分析癌症中的基因融合的新方法,改善低频变异的结合和丰富. 改进的技术使得超快速,高度敏感的纳米孔测序用于癌症诊断和药物开发.

关键词:
基因融合检测检测 基因融合检测基因测序是指基因的测序.结合的收益率 结合的收益率选择性丰富是一种选择性丰富.热力学是一种热力学.

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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
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