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眼部感染中的抗菌素耐药性:一篇综述
Maria Cabrera-Aguas1,2, Ngozi Chidi-Egboka1, Himal Kandel1
1Faculty of Medicine and Health, Save Sight Institute, The University of Sydney, Sydney, New South Wales, Australia.
Clinical & experimental ophthalmology
|March 17, 2024
概括
眼部感染中的抗菌素耐药性 (AMR) 正在全球范围内上升,特别是诺基诺耐药性. 眼部抗菌药物管理计划对于打击这种威胁和保护视力至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- 抗菌素耐药性 (AMR) 构成了全球重大公共卫生挑战,影响治疗疗效.
- 世界卫生组织强调需要强有力的监测和研究来解决AMR.
- 眼部感染需要全面的,最新的AMR数据,以有效的临床管理和趋势识别.
研究的目的:
- 提供关于眼睛病原体抗微生物耐药性 (AMR) 趋势的最新概述.
- 审查细菌眼部感染中的AMR,并讨论抗微生物药物管理 (AMS) 计划.
- 突出监测数据对于指导眼科治疗和AMS策略的重要性.
主要方法:
- 对常见眼睛病原体抗微生物耐药性的现有研究和监测计划的审查.
- 对Pseudomonas aeruginosa,Staphylococcus spp.,Streptococcus pneumoniae和Haemophilus influenzae等关键生物体的耐药性模式的分析.
- 检查结膜炎和角膜炎中对诺基诺和甲基西林耐药性的趋势.
主要成果:
- 观察到基诺抗性增加,特别是在亚洲和北美.
- 结膜炎:ARMOR研究报告说,美国的西普洛素耐药性略有下降.
- 角膜炎:甲素耐药性稳定于黄金色杆菌和CoNS;全球对MRSA的抗性降低. 新兴的甲素和多药耐药性需要监测.
结论:
- 抗微生物药物管理 (AMS) 计划对于缓解AMR和改善患者结果至关重要.
- 有效的AMS依赖于当前的AMR监测数据.
- 眼科必须积极支持监测,并建立AMS,以防止AMR导致的视力损失.
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