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Updated: Jun 30, 2025

Isolation of Mouse Interstitial Valve Cells to Study the Calcification of the Aortic Valve In Vitro
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Isolation of Mouse Interstitial Valve Cells to Study the Calcification of the Aortic Valve In Vitro

Published on: May 10, 2021

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综合性基因组分析确定了形大动脉狭窄症的候选因果基因,涉及组织特异性调节

Sébastien Thériault1,2, Zhonglin Li3, Erik Abner4

  • 1Institut universitaire de cardiologie et de pneumologie de Québec-Université Laval, Quebec City, QC, Canada. sebastien.theriault@criucpq.ulaval.ca.

Nature communications
|March 18, 2024
PubMed
概括

这项研究确定了32个与状大动脉狭窄症 (CAVS) 相关的遗传区域,发现了20个新的位置. 这些发现突出了TWIST1,并表明脂蛋白,血压和炎症在开发新的CAVS疗法中的作用.

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