最少侵入性微型硬化成形 (MIMS) 程序在治疗开角玻璃眼的治疗
Lilit Voskanyan1,2, Iqbal Ike K Ahmed3, Assaf Gershoni4,5
1Ophthalmological Center after S.V. Malayan, Yerevan, Armenia.
BMC ophthalmology
|March 18, 2024
概括
最少侵入性微型硬化术 (MIMS) 程序有效降低开角玻璃眼患者的眼内压力. 这种安全和快速的手术选择显示出对轻度至中度病例的管理有希望.
科学领域:
- 眼科医生 眼科 眼科
- 视光眼管理 视光眼管理
- 最少侵入性的手术
背景情况:
- 开角玻璃眼 (OAG) 和脱皮玻璃眼是不可逆转视力丧失的常见原因.
- 失控的眼内压力 (IOP) 尽管局部药物需要替代治疗策略.
- 最少侵入性微型硬化术 (MIMS) 程序被评估为其安全性和有效性.
研究的目的:
- 评估MIMS程序的安全性和有效性,用于管理不受控制的开角玻璃眼.
- 评估MIMS在52周内降低内脏压力的效果和成功率.
- 识别和记录与程序相关的并发症和不良事件.
主要方法:
- 一项前性,开放性,单臂研究包括120名患有OAG或脱皮性玻璃眼的成年患者.
- 内MIMS手术,有或没有法化,是在下结膜Mitomycin C后进行的.
- 患者被跟踪了52周,成功的定义是IOP≤21mmHg和/或≥20%的IOP降低.
主要成果:
- 52周后,平均内血压下降了38%,从27.9 mmHg降至17.5 mmHg (P < 0.001).
- 在82.1%的患者中取得了合格的成功,在70.5%的患者中取得了完全的成功.
- 没有报告严重的不良事件或设备故障;常见事件包括虹膜堵塞和短暂的IOP尖峰.
结论:
- MIMS手术是一种安全,简单,快速的微创性玻璃眼手术.
- 该程序在减轻轻度和中度不受控制的开角绿内障患者的内腔焦点方面表现出显著的有效性.
- 对于未得到充分控制的玻璃眼患者来说,MIMS提供了一个可行的治疗选择.
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