怀孕早期的维生素D营养状况及其与周周多种微量营养素补充的关系
Chun-Jing Wang1, Zhao Li2,3, Yin-Xiao Bai2,3
1Tongzhou Maternal & Child Health Hospital of Beijing, Beijing, China.
Asia Pacific journal of clinical nutrition
|March 18, 2024
概括
孕期多种微量营养素 (MM) 补充剂显著减少了北京妇女在怀孕早期的维生素D缺乏和不足. 这种补充对于改善母亲的维生素D营养状况至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 维生素D缺乏和不足在孕妇中很普遍.
- 怀孕早期是对母亲和胎儿健康的关键时期.
- 评估维生素D营养状况 (VDN) 对于优化妊娠结果至关重要.
研究的目的:
- 评估怀孕早期孕妇的维生素D营养状况 (VDN).
- 调查周周多重微量营养素 (MM) 补充对VDN的影响.
主要方法:
- 在北京 (2018年) 的4978名孕妇数据的回顾性分析.
- 仅服用叶酸 (FA) 和多种微量营养素 (MMs) 的女性之间的VDN比较.
- 用于估计MM补充剂和维生素D缺乏/不足之间的关联的物流回归模型.
主要成果:
- 怀孕早期维生素D的平均度为18.6 ng/mL,缺乏率高 (31.6%) 和不足 (60.5%).
- 与单独服用FA相比,MM补充与维生素D缺乏 (aOR 0.17) 和缺乏 (aOR 0.25) 的几率明显降低.
- 更高的合规性,更长的持续时间和使用MM的频率增加与较低的缺陷率相关. 在寒冷的月份,MM补充剂显示出显著的效果.
结论:
- 北京的孕妇在怀孕早期表现出低血清维生素D水平.
- 用多种微量营养素 (MMs) 进行孕期补充有效改善维生素D营养状况.
- 补充MM是一种可行的策略,可以缓解怀孕早期的维生素D缺乏.
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