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Updated: Jun 30, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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O-GlcNAc通过EZH2调节肺纤维细胞中的抗纤维基因

Qiuming P Wu1, Shia Vang1, Jennifer Q Zhou1,2

  • 1Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Journal of cellular and molecular medicine
|March 18, 2024
PubMed
概括

与O相关的N-乙糖胺 (O-GlcNAc) 修饰调节肺纤维细胞中的抗纤维基因. 抑制O-GlcNAc转移酶 (OGT) 在异常性肺纤维化 (IPF) 和TGF-β1治疗细胞中恢复抗纤维化基因表达.

关键词:
在Cox2Cox2Cox2Cox2在 EZH2 中使用.H3K27me3 在线阅读这就是Hmox1的意思.这就是O-GLcNAcc.其他 OGT 产品.在TGF-β1中.肺部纤维细胞细胞.肺部纤维化 肺部纤维化

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