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通过分子模拟来解开SARS-CoV-2变体的结合机制

Shin-Pon Ju1,2, Yung-Cheng Yang1, Hsing-Yin Chen2

  • 1Department of Mechanical and Electro-Mechanical Engineering, National Sun Yat-sen University, Kaohsiung 804, Taiwan.

Heliyon
|March 18, 2024
PubMed
概括

欧米克朗和三角洲变种比野生型的SARS-CoV-2对人类的ACE2受体具有更强的结合. 计算建模揭示突变增强结合亲和力和传染性,告知疫苗和治疗开发对进化的变体.

关键词:
在ACE2受体.结合性亲缘关系是一种结合性亲缘关系.同一个粒度的分子动力学.这就是SARS-CoV-2病毒.尖蛋白质是一种尖蛋白质.变种 变种 变种 变种

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