自免疫性肝炎管理的进展:未来指南的前景
1Liver Transplantation Group, Santa Casa de Porto Alegre, Porto Alegre 90035-070, RS, Brazil. mmucenic@gmail.com.
World journal of hepatology
|March 18, 2024
概括
普雷迪尼松在自身免疫性肝炎中显示出更高的完整生化反应 (CBR) 率,而不是布塞尼德. 菌酸莫菲蒂尔 (MMF) 可能为对AZA不耐受的患者提供阿扎西奥普林 (AZA) 的优质替代品.
科学领域:
- 肝病学和免疫学 肝病学和免疫学
- 胃肠病学 胃肠病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 自体免疫性肝炎 (AIH) 的第一线治疗通常包括单独或与阿扎西奥普林 (AZA) 的普雷迪松或普雷迪索隆.
- 布德索尼德是一种可选的第一线治疗方法,特别是对于非肝硬化患者,尽管研究设计可能有利于其疗效.
- 氨酸莫菲提尔 (MMF) 建议用于AZA不耐受患者,但证据有限,主要来自病例系列.
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