Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

RNA-seq03:21

RNA-seq

10.0K
RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
10.0K
Genomics02:02

Genomics

36.3K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
36.3K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Atlas-Level Single-Cell and Spatial Transcriptomics Data Integration via PRIME.

bioRxiv : the preprint server for biology·2026
Same author

Virus Elimination by Thermotherapy Combined with Meristem Culture.

Methods in molecular biology (Clifton, N.J.)·2026
Same author

The dehydrin protein COR15 enhances antiviral RNA silencing by preventing viral protein-mediated SGS3 degradation and promoting SGS3 condensate formation.

Plant communications·2026
Same author

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Molecular and histopathological mechanisms underlying pesticide-induced disruption of the hypothalamic-pituitary-gonadal axis in Japanese medaka.

Journal of hazardous materials·2026
Same author

MetaPaCS: A Novel Meta-Learning Framework for Pancreatic Cancer Subtype Identification.

bioRxiv : the preprint server for biology·2026
Same journal

Navigating the labyrinth of drugging the disordered.

Biophysical reviews·2026
Same journal

<i>Biophysical Reviews</i>: a forum for publication of review articles from the international biophysics community.

Biophysical reviews·2026
Same journal

Mitochondrial potassium channels: mitochondria-specific mechanism of regulation.

Biophysical reviews·2026
Same journal

Biomolecular condensates in living systems: from function to disease. What to do next.

Biophysical reviews·2026
Same journal

Astrocyte morphology: complex or trivial?

Biophysical reviews·2026
Same journal

Correction to: A quest for greater thermodynamic rigour in the quantitative characterization of protein self-association by direct assessment of sedimentation equilibrium distributions.

Biophysical reviews·2026
查看所有相关文章

相关实验视频

Updated: Jun 30, 2025

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
08:51

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

1.2K

在单细胞多模式测序和多omics数据集成方面的进展.

Xuefei Wang1, Xinchao Wu1, Ni Hong1

  • 1Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China.

Biophysical reviews
|March 18, 2024
PubMed
概括
此摘要是机器生成的。

单细胞多式欧米克技术从一个细胞中对多个分子层进行分析,克服信息碎片化. 整合这些数据将建立一个全面的细胞地图,以了解基因调节和疾病.

关键词:
数据集成数据集成.多个omics的多个omics.多omics数据集成多omics数据集成单细胞多式联通电信是单细胞多式联通电信.单细胞测序是一种单细胞测序.

更多相关视频

Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq
06:24

Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq

Published on: March 12, 2021

3.6K
An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing
10:00

An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing

Published on: May 23, 2018

17.6K

相关实验视频

Last Updated: Jun 30, 2025

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
08:51

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

1.2K
Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq
06:24

Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq

Published on: March 12, 2021

3.6K
An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing
10:00

An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing

Published on: May 23, 2018

17.6K

科学领域:

  • 单细胞生物学 单细胞生物学
  • 多omics数据集成多omics数据集成
  • 基因组学和表观基因组学

背景情况:

  • 单细胞测序的进步使细胞异质性的剖析成为可能.
  • 单组学方法提供了碎片化的信息,限制了全面的细胞状态分析.
  • 需要采用综合方法来捕获完整的细胞信息.

研究的目的:

  • 审查单细胞多式联络的实验方法.
  • 总结用于多omics数据集成的计算方法.
  • 讨论单细胞多组学领域的未来方向.

主要方法:

  • 来自单细胞的基因组,转录组,表观基因组和蛋白质组的联合分析实验技术的概述.
  • 用于整合多种单细胞欧米克数据集的计算策略的摘要.
  • 讨论数据整合的挑战和机遇.

主要成果:

  • 单细胞多式联络使得分子层的同时研究成为可能.
  • 多omics数据的整合揭示了基因组/表观遗传变化和基因表达/翻译之间的联系.
  • 在单细胞分辨率下发现疾病致病机制的潜力.

结论:

  • 单细胞多式欧米克技术提供了对细胞状态的整体视图.
  • 数据整合对于充分利用多领域数据的全部潜力至关重要.
  • 未来,公共多主题数据的整合将使一个全面的细胞地图成为可能.