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Updated: Jun 30, 2025

Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage
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Published on: January 31, 2018

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在人类细胞中,PARP13在基底和抗病毒状态下对转录组进行调节

Veronica F Busa1,2, Yoshinari Ando1, Stefan Aigner3,4,5

  • 1Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.

iScience
|March 18, 2024
PubMed
概括

RNA结合蛋白PARP13对于抗病毒防御至关重要,它调节RNA稳定性和基因表达. 这项研究揭示了PARP13如何通过影响ISGylation机制来支持抗病毒途径,从而为细胞的感染做好准备.

关键词:
细胞生物学 细胞生物学免疫反应的免疫反应.分子生物学分子生物学

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