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Updated: Jun 30, 2025

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通过准TBK1,TRIM28促进了I型干扰素的激活

Fang Hua1, Tim Nass1, Kislay Parvatiyar1

  • 1Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, United States.

Frontiers in immunology
|March 18, 2024
PubMed
概括

含有28 (TRIM28) 的三部分基因通过调节TBK1信号来促进抗病毒免疫反应的激活. TRIM28对于宿主防御病毒感染至关重要,因为它缺少会损害干扰素的产生,增加对病毒的敏感性.

关键词:
在TBK1中,在 TRIM2828 中,模式识别受体 (PRR) 是一种模式识别受体.包含28个三个部分的图案.第一种类型的干扰素 (IFN)

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