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Updated: Jun 30, 2025

Quantifying Agonist Activity at G Protein-coupled Receptors
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分析增加M1-AChR受体激活剂和对抗剂分子体积所引起的影响:一个结构和计算研究

Wilber Montejo-López1, Raúl Sampieri-Cabrera2, María Inés Nicolás-Vázquez1

  • 1Departamento de Ciencias Químicas, Facultad de Estudios Superiores Cuautitlán Campo 1, Universidad Nacional Autónoma de México Avenida 1o de Mayo s/n, Colonia Santa María las Torres Cuautitlán Izcalli Estado de Mexico 54740 Mexico wmontejo61@gmail.com nicovain@yahoo.com.mx.

RSC advances
|March 18, 2024
PubMed
概括

量化结构-活性关系 (QSAR) 模型是为M1肌糖乙胆受体 (M1-AChR) 激素和抗剂开发的. 干体积影响M1-AChR结合能量和亲和力,有助于开发用于阿尔茨海默氏症和精神分裂症的药物.

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