在患有Hba1c升高的患者中,临床下多神经病变的存在
Yılmaz Çetinkaya1, Güler Özdemir2, Buse Rahime Hasirci Bayir1
1Haydarpaşa Numune Training and Resarch Hospital, Department of Neurology, İstanbul, Turkey.
Noro psikiyatri arsivi
|March 18, 2024
概括
血红蛋白A1c (HbA1c) 升高的无症状个体表现出外周神经系统的参与,表明早期的神经损伤. 及时的血糖控制对于预防这些患者出现多神经病的发展至关重要.
科学领域:
- 神经学 神经学
- 内分泌学 在内分泌学.
- 临床医学 临床医学
背景情况:
- 在无症状个体中血红蛋白A1c (HbA1c) 的亚临床升高可能表明早期代谢功能障碍.
- 周围神经病变是糖尿病的常见并发症,但其在糖尿病前期的发病情况不太了解.
研究的目的:
- 为了研究高HbA1c的无症状个体与多神经病变的发生之间的关系.
- 为了比较患有亚临床HbA1c升高的人与正常血糖控制者的神经传导参数.
主要方法:
- 一项涉及30名患有亚临床HbA1c升高的女性患者和30名正常血糖健康女性对照者的比较研究.
- 所有参与者都进行了神经传导检查,以评估周围神经功能.
主要成果:
- 与对照组相比,在HbA1c升高的组中观察到神经幅度降低 (大腿骨运动,部感觉) (p<0.05).
- 在HbA1c升高组 (p<0.05) 中,观察到远端延迟 (脚部,中部,部运动) 和感觉神经延迟 (部,中部,部) 的增加 (p<0.05).
- 在高HbA1c组 (p<0.05) 中,在外侧,中侧和部感觉神经中发现了下部神经传导速度.
结论:
- 患有亚临床HbA1c升高的无症状个体表现出外周神经系统的参与.
- 建议早期进行血糖控制,以预防高HbA1c患者的神经病变的发展.
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