在HPV阳性老年妇女中,HPV病史
Ruth S Hermansson1,2, Gabriella Lillsunde-Larsson3,4, Gisela Helenius3
1Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
概括
很少有HPV和发育不良的老年妇女有相同感染的病史,这表明人类乳头瘤病毒 (HPV) 在老年妇女中的作用需要进一步研究.
科学领域:
- 妇科 妇科 妇科 妇科
- 病毒学 病毒学
- 在瘤学瘤学.
背景情况:
- 人类乳头瘤病毒 (HPV) 感染是宫发育不良的已知危险因素.
- 较年长的女性 (≥60岁) 的HPV感染的自然史及其与肌肉发育不良的相关性不太清楚.
研究的目的:
- 在60岁及以上的妇女中调查HPV感染的过程.
- 在这个年龄组中确定历史HPV阳性和肌肉发育不良结果之间的关联.
主要方法:
- 该研究包括89名年龄在60-82岁的女性,在2012-2016年期间获得了HPV阳性结果.
- 在档案样本上进行了细胞学,组织学和HPV基因型鉴定 (1999年以前).
主要成果:
- 在纳入时,16名女性患有高度状内皮损伤 (HSIL),34名患有低度状内皮损伤 (LSIL),39名为良性.
- 显著比例的女性患有发育不良或良性结果在历史样本中没有匹配的HPV类型 (范围从25.6%到69.2%负).
结论:
- 被诊断为HPV和肌肉发育不良的老年妇女很少有相同的HPV类型的病史.
- 在老年妇女中,HPV在肌肉发育不良的作用尚不清楚,需要进一步调查.
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