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通过炎症诱导的染色体形状调节免疫信号整合和记忆

Bence Daniel1,2,3,4,5, Andy Y Chen1,6,3,4, Katalin Sandor1,3,4

  • 1Department of Pathology, Stanford University, Stanford, CA, USA.

bioRxiv : the preprint server for biology
|March 18, 2024
PubMed
概括

介质蛋白-4 (IL-4) 重编程巨细胞的3D基因组构造,增强炎症基因表达,并使转录记忆成为可能. 这些3D基因组变化对免疫细胞反应和记忆至关重要.

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