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相关概念视频

Protein Folding01:25

Protein Folding

8.0K
Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.
Protein Structure Is Critical to Its Biological Function
Proteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...
8.0K
Protein Organization01:24

Protein Organization

6.5K
Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence....
6.5K
Protein and Protein Structure02:15

Protein and Protein Structure

79.5K
Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme...
79.5K
Proteins: From Genes to Degradation02:11

Proteins: From Genes to Degradation

12.2K
Within a biological system, the DNA encodes the RNA, and the nucleotide sequence in the RNA further defines the amino acid sequence in the protein. This is referred to as “The Central Dogma of Molecular Biology” - a term coined by Francis Crick.  Central dogma is a firm principle in biology that defines the flow of genetic information within any life form. The two fundamental steps in central dogma are - transcription and translation.
Transcription is the synthesis of RNA...
12.2K
Ribosomes01:27

Ribosomes

7.6K
Ribosomes translate genetic information encoded by messenger RNA (mRNA) into proteins. Both prokaryotic and eukaryotic cells have ribosomes. Cells that synthesize large quantities of protein—such as secretory cells in the human pancreas—can contain millions of ribosomes.
Ribosome Structure and Assembly
Ribosomes are composed of ribosomal RNA (rRNA) and proteins. In eukaryotes, rRNA is transcribed from genes in the nucleolus—a part of the nucleus that specializes in ribosome...
7.6K
Protein and Protein Structures02:15

Protein and Protein Structures

10.4K
10.4K

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相关实验视频

Updated: Jun 30, 2025

Electron Cryotomography of Bacterial Cells
14:23

Electron Cryotomography of Bacterial Cells

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使用虚幻引擎在原子层面上染细胞内部的蛋白质结构.

Muyuan Chen1

  • 1Division of CryoEM and Bioimaging, SSRL, SLAC National Accelerator Laboratory, Stanford University, Menlo Park, CA 94025, USA.

bioRxiv : the preprint server for biology
|March 18, 2024
PubMed
概括

低温电子断层扫描 (CryoET) 允许细胞大分子的近原子分辨率. 一种新的视频游戏引擎方法可以实时可视化这些分子在它们的原生细胞环境中.

科学领域:

  • 细胞和分子生物学 细胞和分子生物学
  • 计算生物学 计算生物学
  • 生物物理学的生物物理.

背景情况:

  • 低温电子断层扫描 (CryoET) 推进了细胞和宏分子结构的确定.
  • 在原子分辨率下可视化复杂的细胞环境仍然是一个重大挑战.
  • 数百万个分子的实时计算染是一个关键障碍.

结论:

  • 视频游戏引擎方法克服了可视化细胞复杂性的计算局限性.
  • 这种方法提高了对宏分子结构及其在现场相互作用的理解.
  • 为生物研究和教育提供了一个强大的新工具.

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