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Updated: Jun 30, 2025

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates
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Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates

Published on: May 9, 2025

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通过非病毒工程和高度复合基编辑来提高CAR-NK细胞的精度

Minjing Wang1,2,3,4, Joshua B Krueger1,2,3, Alexandria K Gilkey1,2,3

  • 1Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.

bioRxiv : the preprint server for biology
|March 18, 2024
PubMed
概括

这项研究介绍了基编辑器 (BE) 用于增强自然杀手 (NK) 细胞,这是一个有前途的免疫疗法. 改造后的NK细胞显示出更好的杀死癌症的能力,为更有效的癌症治疗铺平了道路.

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