相关实验视频

Updated: Jun 30, 2025

Evaluation of LC3-II Release via Extracellular Vesicles in Relation to the Accumulation of Intracellular LC3-positive Vesicles
06:58

Evaluation of LC3-II Release via Extracellular Vesicles in Relation to the Accumulation of Intracellular LC3-positive Vesicles

Published on: October 18, 2024

664

感染HTLV-1的T细胞会通过小的细胞外囊泡引起骨质损失

Nitin Kumar Pokhrel, Amanda Panfil, Haniya Habib

    bioRxiv : the preprint server for biology
    |March 18, 2024
    PubMed
    概括

    人类T细胞白血病病毒1型 (HTLV-1) 感染T细胞释放小细胞外囊泡 (sEV),通过向骨质细胞,导致骨损失,独立于RANKL. 这种机制有助于成人T细胞白血病 (ATL) 的骨解性病变.

    更多相关视频

    Direct Stochastic Optical Reconstruction Microscopy of Extracellular Vesicles in Three Dimensions09:36

    Direct Stochastic Optical Reconstruction Microscopy of Extracellular Vesicles in Three Dimensions

    Published on: August 26, 2021

    3.8K
    Isolation And Dendritic Cell-Uptake of Small Extracellular Vesicles from Echinococcus granulosus09:04

    Isolation And Dendritic Cell-Uptake of Small Extracellular Vesicles from Echinococcus granulosus

    Published on: March 28, 2025

    206

    相关概念视频

    Intralumenal Vesicles and Multivesicular Bodies01:38

    Intralumenal Vesicles and Multivesicular Bodies

    Intraluminal vesicles (ILVs) are small vesicles 50-80 nm in diameter formed during the maturation of early endosomes. A specialized endosome containing numerous ILVs is called a multivesicular body (MVB). ILVs contain internalized molecules such as antigens, nucleic acids, proteins, and metabolites. Some of these molecules are released from the MVBs inside exosomes and are transported to other cells. Other MVBs contain molecules that are retained in the ILVs and are later degraded within the...
    3.5K
    Receptor Downregulation in MVBs01:15

    Receptor Downregulation in MVBs

    Multivesicular bodies (MVBs) are mature endosomes that sort ubiquitinated proteins and then fuse with lysosomes to degrade the sorted proteins. Epidermal growth factor (EGF) and its receptor (EGFR) form a complex that can be internalized through endocytosis, sorted into an MVB, and later degraded.
    The EGFR can initiate signaling pathways that  lead to cell proliferation, migration, and differentiation. Overexpression of EGFR  stimulates cells to proliferate. Excessive  EGFR...
    2.1K