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Updated: Jun 30, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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感冒瘤的保存子集对免疫检查点封锁有反应

Jade Moore1,2, Jim Gkantalis1, Ines Guix1

  • 1Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, USA.

bioRxiv : the preprint server for biology
|March 18, 2024
PubMed
概括

这项研究确定了一种生物标志物 (βAlt),该生物标志物可以预测感冒瘤对免疫检查点阻塞 (ICB) 的反应. 抑制TGFβ可以通过激活自然杀手细胞,将这些瘤转化为ICB反应的瘤.

关键词:
缺少DNA修复的缺陷在TGFβ中,TGFβ是TGFβ.生物标志物 生物标志物免疫检查点封锁封锁自然杀手细胞是自然杀手细胞.

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