Search research articles

关于 JoVE

概览领导团队博客 JoVE 帮助中心

作者

出版流程编辑委员会范围与政策同行评审常见问题投稿

图书馆员

用户评价订阅访问资源图书馆顾问委员会常见问题

研究

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments 存档

教育

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual 教师资源中心教师网站

使用条款与条件

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序

Same author

Evaluating the Performance of Photon- and Electron-Based Fragmentation Methods in Omnitrap-LCMS Analysis of <i>N</i>-Glycopeptides.

Analytical chemistry·2026

Same author

Spatial distribution of the proteome in the human body and in cancers.

Nature·2026

Same author

Integrated proteogenomic and metabolomic profiling of acute myeloid leukemias to identify molecular subtypes and associated therapy targets.

Nature cancer·2026

Same author

Aerobic soil bacteria adapt to hypoxia by hybridizing fermentation with carbon storage.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

Investigating the P450-Mediated Cross-Linking of the Atypical GPA Complestatin Using Alternate Peptide Probes.

The Journal of organic chemistry·2026

Same author

Monocyte Migration Emerges from a Divergent Chemokine Signaling Network.

bioRxiv : the preprint server for biology·2026

Same journal

A human-specific genetic modifier reconfigures large-scale cortical network dynamics underlying behavioral performance.

bioRxiv : the preprint server for biology·2026

Same journal

<i>Staphylococcus aureus</i> uses a eukaryotic-like uridyltransferase to make UDP-GlcNAc for cell wall synthesis.

bioRxiv : the preprint server for biology·2026

Same journal

Dynamic redistribution of eIF4F controls cap-dependent translation initiation.

bioRxiv : the preprint server for biology·2026

Same journal

When does additional information improve accuracy of RNA secondary structure prediction?

bioRxiv : the preprint server for biology·2026

Same journal

Normative brain-state trajectories reveal deviation from healthy aging in Alzheimer's disease.

bioRxiv : the preprint server for biology·2026

Same journal

Noradrenergic infraslow rhythm during sleep is the critical link between heart-rate dynamics and memory consolidation.

bioRxiv : the preprint server for biology·2026

查看所有相关文章

Search research articles

相关实验视频

Updated: Jun 30, 2025

The Application of Open Searching-based Approaches for the Identification of Acinetobacter baumannii O-linked Glycopeptides

The Application of Open Searching-based Approaches for the Identification of Acinetobacter baumannii O-linked Glycopeptides

Published on: November 2, 2021

使用FragPipe-Analyst进行定量蛋白质组学数据的分析和可视化.

Yi Hsiao¹, Haijian Zhang², Ginny Xiaohe Li³

¹Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.

bioRxiv : the preprint server for biology

|March 18, 2024

概括

此摘要是机器生成的。

FragPipe-Analyst是一个新的R闪亮的Web服务器,为定量蛋白质组学数据提供用户友好的下游统计分析和可视化. 它支持各种量化工作流程,并提供更深入的生物学洞察力的高级功能.

关键词:

在AP-MS中使用AP-MS.在FragPipe中使用FragPipe.这是一个 LiP-MS 系统.生物信息学是一种生物信息学.下游分析下游分析这是开源的,开源的.蛋白质的酸化是蛋白质的酸化.软件软件软件软件软件

更多相关视频

Simultaneous Affinity Enrichment of Two Post-Translational Modifications for Quantification and Site Localization

Simultaneous Affinity Enrichment of Two Post-Translational Modifications for Quantification and Site Localization

Published on: February 27, 2020

Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames

Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames

Published on: April 11, 2019

相关实验视频

Last Updated: Jun 30, 2025

The Application of Open Searching-based Approaches for the Identification of Acinetobacter baumannii O-linked Glycopeptides

The Application of Open Searching-based Approaches for the Identification of Acinetobacter baumannii O-linked Glycopeptides

Published on: November 2, 2021

Simultaneous Affinity Enrichment of Two Post-Translational Modifications for Quantification and Site Localization

Simultaneous Affinity Enrichment of Two Post-Translational Modifications for Quantification and Site Localization

Published on: February 27, 2020

Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames

Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames

Published on: April 11, 2019

科学领域:

蛋白质组学是指蛋白质组学.
生物信息学是一种生物信息学.
计算生物学计算生物学

背景情况:

由于其速度和可用性,FragPipe计算蛋白质组学平台被广泛采用.
现有的工作流需要用户友好的工具来下游统计分析和定量蛋白质组学数据的可视化.

研究的目的:

为FragPipe用户开发一个易于使用的下游统计分析和可视化工具.
为主要定量蛋白质组学工作流提供支持.
为数据解释和可视化提供高级功能.

主要方法:

开发了一个名为FragPipe-Analyst的R闪亮的Web服务器.
综合功能用于缺失值赋值,质量控制和集群.
使用Limma实现差异表达式分析,使用Enrichr.进行丰富分析.
创建了一个R包,FragPipeAnalystR,用于高级和特定站点的PTM分析.

主要成果:

FragPipe-Analyst提供了一个用户友好的界面,用于下游蛋白质组学数据分析.
该工具支持无标签量化,TMT和DIA工作流.
FragPipeAnalystR将功能扩展到特定地点的PTM分析.
这两种工具都是开源的,可以免费使用.

结论:

FragPipe-Analyst和FragPipeAnalystR提供了可访问的开源解决方案,用于全面的定量蛋白质组学数据分析.
这些工具通过实现强大的下游统计和可视化方法来增强FragPipe的实用性.