从1998年到2022年发表的关于肠肝轴研究的综合文献计量和可视化分析
Yongtian Wen1,2, Tai Zhang1,2, Beihua Zhang1,2
1Institute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, China.
Heliyon
|March 18, 2024
概括
对肠肝轴的研究正在迅速扩大,过去三年出版物的数量大幅增加. 关键的研究领域包括肠道微生物群,肠道透性和NASH和ALD等肝脏疾病.
科学领域:
- 胃肠病学和肝病学 胃肠学和肝病学
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
背景情况:
- 肠肝轴是胃肠道和肝脏之间的双向通信通道,自1998年提出以来,已经获得了大量的学术关注.
- 许多研究强调了肠道健康和肝功能之间的复杂关系,需要对研究趋势和科学影响进行分析.
研究的目的:
- 为了对过去25年来关于肠肝轴的出版物进行文献分析.
- 确定肠肝轴领域的研究趋势,热点和边界.
- 为未来的研究方向提供全面的概述.
主要方法:
- 从科学网络核心收藏中获取的776篇出版物的图书统计分析.
- 使用可视化软件,包括CiteSpace和VOSviewer.
- 分析出版趋势,有影响力的机构和关键研究主题.
主要成果:
- 关于肠肝轴的出版物出现了持续的上升趋势,在2020-2022年期间出现了显著的激增.
- 中国在出版量方面处于领先地位,而美国在影响力和国际合作方面处于领先地位.
- 突出的研究主题包括肠道微生物群,微生物代谢物,肠道透性,细菌转位,胆酸,非酒精性脂肪肝炎 (NASH) 和酒精性肝病 (ALD).
结论:
- 本文献计量研究提供了25年来肠肝轴研究的第一个基于可视化的概述.
- 未来的研究应该集中在肠道屏障功能,肠道微生物群失生症和宿主代谢上.
- 这些发现是研究人员导航肠肝轴研究的全球趋势的宝贵参考.
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