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Updated: Jun 30, 2025

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
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Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists

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作为17β-Hydroxysteroid脱酶10型的抑制剂的C-3类固醇半导体

Michaela Hanzlova1, Barbora Slavikova2, Marina Morozovova2

  • 1Faculty of Science, Department of Chemistry, University of Hradec Kralove, Rokitanskeho 62, 500 03 Hradec Kralove, Czech Republic.

ACS omega
|March 18, 2024
PubMed
概括

新的类固醇化合物旨在抑制与神经退行性疾病相关的酶17β-HSD10. 化合物22和23显示出强大的抑制作用,而化合物23在没有细胞毒性的细胞环境中显示出有效性.

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