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Updated: May 6, 2026

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通过对原酶修饰增强多臂聚合物的瘤透率

Bo Yu1, Weijie Wang1, Yongmin Zhang1

  • 1MOE Key Laboratory of High Performance Polymer Materials and Technology, State Key Laboratory of Analytical Chemistry for Life Science, and College of Chemistry & Chemical Engineering, Nanjing University, Nanjing, 210093, P.R. China. zhenxu@nju.edu.cn.

Biomaterials science
|March 18, 2024
PubMed
概括

这项研究开发了一种新的共聚合物药物递送系统,可降解瘤细胞外基质,增强纳米药物透率并提高癌症治疗的有效性.

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Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

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Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
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