调节肠道微生物健康的治疗策略:对皮症管理的方法
Shreya Das1, B Preethi1, Sapana Kushwaha2
1Department of Pharmacy, Birla Institute of Technology and Science (BITS), Pilani Campus, Pilani, Rajasthan, India.
Histology and histopathology
|March 18, 2024
概括
肠道微生物群影响肉症,一种肌肉损失的情况. 诸如益生菌,益生菌和特定营养素等干预措施可以改善肠道健康和肌肉功能,提供新的治疗途径.
科学领域:
- 老年学和微生物学
- 肌肉生理学和衰老的过程
- 肠道微生物组研究研究
背景情况:
- 萨尔科佩尼亚是一种与年龄相关的渐进性骨肌肉损失,缺乏确定的治疗方法.
- 肠道微生物失调症越来越多地与各种疾病有关,包括在肌肉健康方面的潜在作用.
- 了解肠道微生物群对肌肉衰老的影响对于开发新的治疗策略至关重要.
研究的目的:
- 审查肠道微生物群和肌肉健康媒介之间的关联.
- 为了将肠道微生物群的影响和代谢物与肉症生物标志物联系起来.
- 描述肠道微生物群对与年龄相关的肌肉健康影响的机制.
主要方法:
- 文献综述侧重于肠道微生物群,代谢物和肉类.
- 营养补充剂 (蛋白质,维生素D,欧米茄-3脂肪酸,肌酸,黄素,,乌尔索酸) 的分析及其对肠道微生物群的影响.
- 检查食纤维,益生菌,益生菌,多和药理干预措施 (FMT,NSAID, ghrelin模仿剂,ACEI,丁酸盐前体).
主要成果:
- 食物干预措施,如纤维,益生菌,益生菌和多,促进有益的微生物,并产生促进健康的代谢物 (例如,SCFA).
- 营养补充剂和特定的食物积极调节肠道微生物群,影响肌肉健康.
- 药理干预可以调节食欲,肠道运动,减少炎症,间接有利于肌肉健康.
结论:
- 肠道微生物群及其代谢物显著影响肉症的发展和进展.
- 涉及营养,补充剂和生活方式变化的多模式治疗策略可以积极影响肠道微生物群和肌肉健康.
- 对肠-肌肉轴的进一步研究对于开发有效的肉类症疗法至关重要.
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