在双动脉与慢性大动脉吐的双动脉中,左心房应变的预后影响
YuTing Tan1,2,3, YuMan Li1,2,3, WenHui Deng1,2,3
1Department of Ultrasound, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei Province China.
Journal of the American Heart Association
|March 18, 2024
概括
损坏的左心房储应变 (LARS) 预测双主动脉患者有主动脉吐的不良结果. 对于风险分层来说,LARS提供了有价值的预后信息.
科学领域:
- 心脏病学 心脏病学
- 心声回声图 (Echocardiography) 是一种心声回声图.
- 心脏成像 - - 心脏成像
背景情况:
- 双主动脉 (BAV) 和显著的主动脉反 (AR) 可以导致左心室扩张功能障碍.
- 左心房储菌株 (LARS) 是一种新兴的成像生物标志物,用于评估腹功能.
研究的目的:
- 调查LARS在BAV和中度至重度至重度AR患者的预后意义.
- 确定LARS是否提供超出已确定的临床和心声学参数的增量预后价值.
主要方法:
- 预计将招募220名患有BAV和显著AR的患者.
- 斑点追踪回声心脏学来得出LARS和左心室全球纵向应变.
- 综合终点:全因死亡率,心力衰竭住院治疗,或大动脉干预.
主要成果:
- 总共有220名患者被分析,其中20.9%在随访期间达到复合终点.
- 在多变量分析中,受损的LARS (<24%) 是复合终点 (aHR,2.08;P=0.036) 的独立预测因子.
- 添加受损的LARS改善了预测模型的全球 χ2 和重新分类准确性.
结论:
- 损伤的LARS是BAV和显著AR患者的显著独立预后预测因素.
- 在临床和其他心声学参数上,LARS提供了增量预后效用.
- 在这种患者群体中,LARS可能是风险分层的一个有价值的工具.
更多相关视频
08:10Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
1.7K
10:39Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding
Published on: August 30, 2024
643
相关概念视频
Heart Valves
14.9K
The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
14.9K
Imbalances in Cardiac Output
3.3K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
3.3K
Mitral Regurgitation I: Introduction
1.3K
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
1.3K
Mitral Stenosis I: Introduction
1.8K
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
1.8K
Aortic Regurgitation I: Introduction
1.6K
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
1.6K
Heart Failure II: Pathophysiology
1.9K
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
1.9K
