肺栓塞反应小组. 描述了第一个36个月的澳大利亚经历
Bapti Roy1,2, Jin-Gun Cho1,3, Luke Baker4
1Department of Respiratory and Sleep Medicine, Westmead Hospital, Sydney, New South Wales, Australia.
Internal medicine journal
|March 18, 2024
概括
肺栓塞反应小组 (PERT) 在澳大利亚是可行的,用于管理高风险患者. 这项研究表明,PERT指导干预改善了结果,结果与国际数据相提并论.
科学领域:
- 心脏病学 心脏病学
- 肺部医学 肺部医学
- 临界护理医学 临界护理医学
背景情况:
- 高/中等风险的肺栓塞 (PE) 与显著的发病率和死亡率有关.
- 由于PE的复杂性,国际指导方针主张使用肺栓塞反应小组 (PERT).
- 澳大利亚没有关于PE管理的PERT结果的数据.
研究的目的:
- 分析澳大利亚高/中等风险PE患者的临床和结局数据,由PERT管理.
- 在澳大利亚环境中评估PERT指导管理的有效性.
主要方法:
- 75名患有高/中等风险PE和PERT参与的患者的回顾性观察研究 (2018年8月 - 2021年7月).
- 在PERT启动时收集的临床和干预数据.
- 评估患者在PERT启动后长达30天的结果,并使用CTPA和TTE比较RV/LV比率.
主要成果:
- 分析了74名患者的数据.
- 在PERT干预后,RV/LV比率显著降低 (CTPA:1.65至1.30,P<0.001;TTE:1.09至0.93,P<0.001).
- 6.8%的全因死亡率,所有死亡都是在7天之内;20%的出血并发症,大多是轻微的.
结论:
- 在澳大利亚大型复杂PE中心中,PERT模型是可行的和有效的.
- 结果与国际PERT数据可比.
- 成功实施需要资源和多学科投入.
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