更新关于BIobank数据共享 (MIABIS) 核心术语的最低信息到第3版
Niina Eklund1, Cäcilia Engels2,3,4, Michael Neumann5
1Finnish Institute for Health and Welfare, Helsinki, Finland.
Biopreservation and biobanking
|March 18, 2024
概括
关于生物库数据共享的最低信息 (MIABIS) 术语被更新到版本3. 这一修订通过包括数据驱动的生物库,非人类样本和网络描述来增强数据共享,提高了研究人员的可用性.
科学领域:
- 生物银行和数据共享
- 生物信息学和术语发展发展
- 生物医学研究基础设施
背景情况:
- 关于生物库数据共享的最低信息 (MIABIS) 是生物库特定的术语,对数据共享至关重要.
- 之前的版本专注于样本级数据 (样本,样本捐赠者,事件),需要更新以包括以数据为中心的生物库.
- 生物银行实践的演变需要更全面的术语来反映各种服务和数据类型.
研究的目的:
- 将MIABIS核心术语修订和更新到第3版.
- 将数据驱动的生物库,非人类样本收集和网络组织属性纳入其中.
- 提高研究人员的友好性,提高MIABIS术语的整体可用性和语义清晰度.
主要方法:
- 涉及9个使用案例,代表了开发过程中的各种生物库,研究和网络.
- 进行了对欧洲生物银行的调查,以了解他们的服务和用户需求.
- 收集和分析研究人员的样本/数据请求,以确定术语调整的需要.
- 与大型专家小组一起反复审查核心术语,以达成共识.
主要成果:
- 现在MIABIS Core v3包含了数据驱动的生物库和数据收集.
- 更新的术语包括生物银行提供的服务和能力,超出了回顾性样本.
- 扩展以适应非人类样本和数据收集,以及网络的组织属性.
- 改进了与个别级别实体 (样本,样本捐赠者,事件) 的协调,以实现最小的,连贯的术语.
结论:
- 通过扩大其范围,MIABIS Core v3显著提高了生物银行数据共享能力.
- 更新后的术语改进了研究人员的可用性,并容纳了更广泛的生物银行模型.
- 修订加强了MIABIS在生物银行领域的内部语义和整体实用性.
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