虚假发现比例的非对称不确定性
Meng Mei1, Tao Yu2, Yuan Jiang1
1Department of Statistics, Oregon State University, Corvallis, OR 97331, United States.
Biometrics
|March 18, 2024
概括
控制错误发现很难与依赖测试统计数据. 这项研究量化了测试统计依赖如何影响错误发现比例 (FDP) 变异,改善了FDP估计质量评估.
科学领域:
- 统计 统计 统计 统计
- 统计推理 统计推理
- 假设测试 假设测试
背景情况:
- 在多次测试中控制错误发现是具有挑战性的,特别是在依赖测试统计数据的情况下.
- 现有的方法通常假设虚假发现比例 (FDP) 估计和一致性的依赖性较弱.
- 即使在弱依赖的情况下,依赖结构对FDP估计差异的影响也未被充分理解.
研究的目的:
- 量化错误发现比例 (FDP) 估计的变化.
- 调查依赖结构对FDP的非对称方差的影响.
- 在多重测试中提供FDP估计质量的更全面的评估.
主要方法:
- 导出虚假发现比例 (FDP) 的非对称扩张.
- 分析各种依赖结构对FDP的非对称方差的影响.
- 假设测试统计数据的弱依赖和正常分布.
主要成果:
- 即使在弱依赖下,FDP的非对称变异也受到依赖结构的显著影响.
- 量化这种变化对于评估FDP估计的可靠性至关重要.
- 依赖结构在FDP估计的准确性中起着关键作用.
结论:
- 报告FDP的平均值和差异估计提供了对多个测试结果的更可靠的评估.
- 了解FDP变异性可以提高对统计学意义的解释.
- 这项研究解决了在依赖测试统计数据下量化FDP估计质量的差距.
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