MRI (DWI和DCE) 与腺多形腺瘤细胞性之间的相关性
Laura Monestier1, Jean Del Grande2, Ralph Haddad1
1Department of Oto-Rhino-Laryngology-Head and Neck Surgery, La Conception University Hospital, AP-HM, Aix-Marseille University, Marseille, France.
概括
使用明显扩散系数 (ADC) 值的手术前MRI可以预测低细胞状形腺瘤. 这有助于在手术前识别具有更高复发风险的瘤.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 状形腺瘤具有复发风险,特别是低细胞亚型.
- 准确的瘤组织学的术前表征对于治疗规划至关重要.
研究的目的:
- 调查扩散和 perfusion MRI 序列是否可以在手术前表征 hypocellular parotid 形腺瘤.
- 为了将MRI发现与组织学亚型相关联.
主要方法:
- 在2010年至2020年间对97名手术患者进行了回顾性分析.
- 组织学分类为低细胞,古典和高细胞亚型.
- 使用单变量和多变量分析,MRI参数 (扩散, perfusion) 与组织学的相关性.
主要成果:
- 低细胞亚型与古典和高细胞亚型相比显示明显更高的明显扩散系数 (ADC) 值 (p < 0.0001).
- 多变量分析表明ADCmean> 1.88 × 10−3 mm2/s预测低细胞亚型,准确度为79%,特异性为94%,预测值为96% (p < 0.001).
结论:
- 手术前的MRI,特别是ADC值,可以预测状形腺瘤的组织学亚型.
- 建议进行进一步的前性多中心研究,以在更大的队列中验证这些发现.
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