相关实验视频

Updated: Jun 30, 2025

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages
06:52

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages

Published on: May 21, 2018

10.7K

败血症中的NLRP3炎症组:不要忽视小步骤 - - 它们可以产生很大的影响!

Felicie Belicard1,2, Karin Tarte1,2, Jean-Marc Tadié1,2,3

  • 1Department of Infectious Diseases and Intensive Care Unit, CHU Rennes, 35000 Rennes, France.

Journal of leukocyte biology
|March 18, 2024
PubMed
概括

在败血症中持续的NLRP3激活驱动了髓质衍生抑制细胞的扩张,并提高了Interleukin-10 (IL-10) 水平. 这突显了败血症引起的免疫失调的关键途径.

关键词:
在NLRP3炎症酶体中,NLRP3炎症免疫抑制是一种免疫抑制.这是一种血症.

更多相关视频

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells09:04

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells

Published on: May 22, 2014

20.9K
A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats05:56

A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats

Published on: February 20, 2021

2.1K

相关概念视频

Regulation of the Unfolded Protein Response01:31

Regulation of the Unfolded Protein Response

Inositol-requiring kinase one or IRE1 is the most conserved eukaryotic unfolded protein response (UPR) receptor. It is a type I transmembrane protein kinase receptor with a distinctive site-specific RNase activity. As the binding mechanics of the misfolded proteins with the N-terminal domain of IRE-1 are unclear, three binding models — direct, indirect, and allosteric -- are proposed for receptor activation. Nevertheless, it is known that once a misfolded protein associates with IRE1, it...
2.4K