成年癌症患者的疫苗接种:ASCO指南
Mini Kamboj1, Kari Bohlke2, Deana M Baptiste3
1Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, NY.
概括
针对癌症的成年人接种疫苗对于限制感染严重程度和预防疾病至关重要. 优化疫苗接种状态,包括及时给予和再接种疫苗,是癌症护理的关键组成部分.
科学领域:
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
- 疫苗学 疫苗学 疫苗学
背景情况:
- 患有固体瘤或血液恶性瘤的成年人患有传染性并发症的风险增加.
- 现有的癌症患者疫苗接种指南需要根据最近的证据进行更新.
研究的目的:
- 为成年癌症患者接种疫苗提供基于证据的建议.
- 引导医疗保健提供者优化癌症患者及其接触者的疫苗接种状态.
主要方法:
- 从2013年到2023年对系统性审查,RCT和非随机化研究的系统性文献综述.
- 包括关于癌症患者和家庭接触者的疫苗有效性和安全性的研究.
- 由ASCO召开专家小组,审查证据并提出建议.
主要成果:
- 包括102个出版物:24个系统审查,14个RCT和64个非随机研究.
- 大多数证据都集中在该人群中COVID-19疫苗的有效性和安全性上.
- 证据还涉及其他相关的免疫功能低下个体的疫苗.
结论:
- 优化疫苗接种状态是癌症护理的关键方面,旨在减少感染严重程度和预防疾病.
- 建议包括记录疫苗接种情况,及时接种疫苗,以及移植后适当的再接种或治疗.
- 医疗保健提供者之间的合作和家庭接触者的疫苗接种对于全面的保护至关重要.
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