在Lisdexamfetamine治疗中测量客观和主观睡眠 治疗急性甲基胺戒断:可行性研究
Liam S Acheson1,2,3, Christopher Gordon4,5, Rebecca McKetin1
1The National Drug and Alcohol Research Centre (NDARC), The University of New South Wales, Sydney, New South Wales, Australia.
European addiction research
|March 18, 2024
概括
行为摄影和睡眠日记是可行的测量睡眠在甲基胺戒断期间,显示低参与者负担. 与主观睡眠日记报告相比,客观行动图显示了显著的差异.
科学领域:
- 睡眠医学 睡眠医学
- 成研究 研究成研究
- 临床神经科学 临床神经科学
背景情况:
- 在使用和戒除甲基胺 (MA) 的人群中,睡眠障碍很普遍.
- 在这个人群中,客观的睡眠和清醒测量的可行性仍未得到充分研究.
- 行为摄影提供了一个非侵入性,客观的睡眠评估方法,具有确定的有效性.
研究的目的:
- 评估合并动图和睡眠日记的可行性和实用性,用于在MA撤销期间监测睡眠.
- 评估参与者的坚持和与客观和主观睡眠监测工具相关的负担.
主要方法:
- 一项可行性和实用性研究,涉及10名接受MA撤回的住院患者.
- 参与者使用了动图仪器 (Philips Actiwatch 2) 并完成了7天的每日睡眠日记.
- 采访是为了收集有关设备和日记可用性的定性反.
主要成果:
- 动图和睡眠日记是可行的,没有过早的设备移除和低报告的参与者负担.
- 客观动图显示平均每日睡眠时间为568分钟,入睡的延迟时间为22.4分钟,入睡后醒 (WASO) 为75.2分钟,睡眠效率为83.6%.
- 睡眠日记显著低于报告的睡眠时间 (56分钟少) 和WASO (47分钟少) 与动图相比 (p < 0.008).
结论:
- 连续动图是一种可行的,低负荷的方法,用于在MA撤销时客观地评估睡眠和清醒状态.
- 主观的睡眠日记报告与客观的行为摄影测量之间存在重大差异.
- 需要进一步的研究来详细探讨这些自我报告和客观测量的差异.
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