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使用不同治疗方式的1型糖尿病儿童和青少年的葡萄糖计量和设备满意度:一个多中心的真实世界观察性研究
Valentino Cherubini1, Andrea Fargalli2, Claudia Arnaldi3
1Department of Women's and Children's Health, Salesi Hospital, 60123 Ancona, Italy.
Diabetes research and clinical practice
|March 18, 2024
概括
自动注射胰岛素 (AID) 系统显著改善了儿童和青少年1型糖尿病的血糖控制和设备满意度. 在现实世界中使用AID系统可以减少糖尿病的影响,提高生活质量.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 代谢障碍 代谢障碍 代谢障碍
- 糖尿病 技术 技术
背景情况:
- 在儿科群体中1型糖尿病 (T1D) 的管理需要持续监测和治疗调整.
- 存在各种糖尿病治疗方法,包括多次每日注射 (MDI) 与血糖监测 (SMBG) 或持续血糖监测 (CGM),传感器增强疗法和自动胰岛素输送 (AID) 系统.
- 评估这些模式的现实结果和患者满意度对于优化T1D护理至关重要.
研究的目的:
- 用不同的治疗策略,评估意大利1型糖尿病儿童和青少年的代谢结果,糖尿病负担和设备满意度.
- 在现实生活环境中比较各种糖尿病管理技术的有效性.
主要方法:
- 一个多中心,全国性的,横截面研究招募了1464名T1D参与者.
- 分析的治疗方式包括MDI + SMBG,MDI + CGM,传感器增强疗法,预测性低血糖管理,混合闭环 (HCL) 和高级混合闭环 (AHCL).
- 意大利版本的糖尿病影响和设备满意度表 (DIDS) 调查问卷评估了与健康有关的生活质量.
主要成果:
- 使用AID系统的患者获得了更好的血糖控制 (HbA1c ≤6.5%) 并在目标葡萄糖范围 (70-180 mg/dL) 内的时间更长.
- 与其他方式相比,AID系统与更高的设备满意度和降低糖尿病影响有关.
- 除了MDI + CGM外,所有模式都改善了与MDI + CGM相比的设备满意度;HCL和AHCL显示糖尿病影响低于MDI + CGM.
结论:
- 在小儿T1D患者中,AID系统的现实应用导致改善血糖控制和增加设备满意度.
- 援助系统有效地减少了糖尿病的负担,并提高了T1D年轻人的生活质量.
- 这些发现支持将AID系统整合到常规糖尿病管理中,以改善患者的治疗结果.
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