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Updated: Jun 30, 2025

Rapid and Efficient Spatiotemporal Monitoring of Normal and Aberrant Cytosine Methylation within Intact Zebrafish Embryos
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Rapid and Efficient Spatiotemporal Monitoring of Normal and Aberrant Cytosine Methylation within Intact Zebrafish Embryos

Published on: August 18, 2022

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异常的DNA甲基化扭曲了非典型的形/形瘤的发育轨迹

Meeri Pekkarinen1, Kristiina Nordfors2,3,4, Joonas Uusi-Mäkelä1

  • 1Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland.

Life science alliance
|March 18, 2024
PubMed
概括

非典型的甲状腺/状腺瘤 (AT/RTs) 显示出独特的DNA高甲基化,抑制神经发育基因. 这种表观遗传变化影响了先驱转录因子的活动,导致儿科脑瘤恶性并阻止细胞分化.

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