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Updated: Jun 30, 2025

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T细胞激活有助于净化对血液中MELAS相关的病原体变异m.3243A>G的选择

Melissa A Walker1,2,3, Shuqiang Li3,4,5, Kenneth J Livak4,5

  • 1Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.

Journal of inherited metabolic disease
|March 18, 2024
PubMed
概括

具有m.3243A>G线粒体变异的T细胞在激活后显示水平降低. 这表明T细胞激活驱动对高变异异质细胞进行净化选择.

关键词:
梅拉斯 (MELAS) 是一种葡萄酒.在中期,中期.在T细胞激活过程中,不同质体质的异质体.线粒体中的线粒体.我们的mtDNA mtDNA

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