在无症状个体中,心脏代谢和甘油三糖指数与左心室透静功能的关联
Runyu Ye1, Xin Zhang1, Zhipeng Zhang1
1Department of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Nutrition, metabolism, and cardiovascular diseases : NMCD
|March 18, 2024
概括
心脏代谢指数 (CMI) 和甘油三糖 (TyG) 有效地识别左心室扩张性功能障碍 (LVDD),特别是在女性中. 这些简单的标记物可以在例行检查期间帮助早期检测.
科学领域:
- 心脏病学 心脏病学
- 代谢健康 代谢健康
- 诊断标记物 诊断标记物
背景情况:
- 肥胖和胰岛素抵抗与左心室透静功能障碍 (LVDD) 和心力衰竭风险有关.
- 心脏代谢指数 (CMI) 和甘油三糖 (TyG) 是内脏肥胖和胰岛素抵抗的新兴标志物.
研究的目的:
- 评估CMI和TyG在识别LVDD的个体中的临床实用性.
- 评估CMI,TyG和透气参数之间的关联.
主要方法:
- 1898个无症状个体的横截面研究.
- 包括人体测量测量,血清生物化学分析和心声回声.
- 多重线性回归和多变量后勤分析的应用.
主要成果:
- CMI和TyG是女性腹筋参数的独立决定因素.
- 随着CMI (女性) 和TyG (两性) 的四分位数较高,LVDD风险增加.
- 在女性中,CMI和TyG都显示了类似的歧视值,在男性中表现优于它们的实用性.
结论:
- 在初级保健中,CMI和TyG显示为可访问的工具,用于在初级保健中检测LVDD,特别是对于女性来说.
- 在资源有限的环境中,CMI为LVDD查提供了更简单的替代方案.
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