2019年世卫组织心血管疾病风险预测图在撒哈拉以南非洲东部非实验室基础的表现
Anderson Bendera1, Keiko Nakamura1, Kaoruko Seino1
1Department of Global Health Entrepreneurship, Division of Public Health, Tokyo Medical and Dental University, Tokyo, Japan.
Nutrition, metabolism, and cardiovascular diseases : NMCD
|March 18, 2024
概括
更新的非实验室基础心血管疾病 (CVD) 风险图适用于东撒哈拉以南非洲没有糖尿病的一般人群. 然而,对于糖尿病患者来说,建议进行实验室评估,以防止低估心血管疾病风险.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 心血管疾病研究研究
背景情况:
- 世界卫生组织 (WHO) 在2019年发布了更新的心血管疾病 (CVD) 风险预测图表,涵盖了全球21个地区.
- 准确的心血管疾病风险评估对于公共卫生干预至关重要,特别是在资源有限的地区.
研究的目的:
- 评估更新的世卫组织非实验室基础心血管疾病风险预测图表的性能.
- 为了将其准确性与撒哈拉以南非洲东部的实验室图表进行比较.
- 评估不同葡萄糖耐受性状态的表现:正常血糖,禁食葡萄糖受损 (IFG) 和糖尿病.
主要方法:
- 利用了世卫组织在撒哈拉以南非洲东部 (2012-2017年) 进行的六次STEPS调查的数据.
- 包括9857名年龄在40-69岁之间的参与者,以前没有心血管疾病史.
- 使用布兰德-阿尔特曼图表和科恩卡帕的非实验室和实验室图表之间的评估一致性.
主要成果:
- 两个图表类型的聚合10年心血管疾病风险中位数为3%.
- 不基于实验室的图表低估了57.6%的糖尿病患者心血管疾病风险.
- 一致性很高 (91.3%),但根据葡萄糖状况的不同而有所不同 (Kappa:0.79正常血糖,0.78 IFG,0.43糖尿病).
结论:
- 非实验室基础的图表适用于该地区在没有糖尿病的一般人口中估计心血管疾病风险.
- 基于实验室的风险评估对于糖尿病患者来说至关重要,以确保准确的CVD风险评估.
- 这些发现支持资源意识的CVD风险分层策略.
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