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Updated: Jun 30, 2025

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在EGFRL858R诱导的肺癌进展过程中,PTEN降低NR2F1的表达,以抑制纤维生成

Thi Thanh Truc Tran1, Jan-Jong Hung2

  • 1Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan, Taiwan.

Cell death & disease
|March 19, 2024
PubMed
概括

瘤抑制剂PTEN通过差异调节EGFR驱动的肺癌. 失去PTEN通过NR2F1通过升高调节纤维生成基因促进支气管增生,而PTEN在KRAS突变肺癌中起着瘤基因的作用.

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