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Updated: Jun 30, 2025

In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol
08:20

In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol

Published on: December 30, 2016

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费里重链支持调节性T细胞系的稳定性和功能

Qian Wu1,2, Ana Rita Carlos1,3, Faouzi Braza1

  • 1Instituto Gulbenkian de Ciência, Oeiras, Portugal.

The EMBO journal
|March 19, 2024
PubMed
概括

调节性T (TREG) 细胞需要铁通过费里重链 (FTH) 进行调节,以保持稳定. FTH支持FOXP3基因去甲基化,这对TREG细胞功能和免疫平衡至关重要.

关键词:
这是FOXP3P3的.费里重链 费里重链铁的新陈代谢 铁的新陈代谢监管T 细胞 监管T 细胞十个十一个转位酶.

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