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Updated: Jun 30, 2025

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
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Published on: January 19, 2017

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由于肥胖导致的AMPK抑制驱动了通过ATF5-POLG轴的卵细胞mtDNA异质体

Yanting Chen1,2, Guiling Ma1,2, Yang Gai1

  • 1National Center for Internatinal Research on Animal Gut Nutrition, Jingsu Key Laboratory of Gastrointestinal Nutrition and Animal Health, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, 210095, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|March 19, 2024
PubMed
概括

女性肥胖会降低卵子线粒体DNA (mtDNA) 质量,增加突变,损害生育能力. AMPK激活可以抵消这些负面影响,改善肥胖女性的卵成熟和线粒体功能.

关键词:
这就是AMPKK.女性肥胖女性肥胖问题成熟的卵子细胞成熟.在 mtDNA 异质体中.

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