无线和无导管膀压力和体积传感器
Steve J A Majerus1,2, Brett Hanzlicek2, Yaneev Hacohen1,3
1Dept. of Electrical, Computer, and Systems Engineering, Case Western Reserve University, OH, USA.
概括
一种新的植入式设备,意识活动的泌尿学监测器 (UroMOCA),可以在有意识的动物中持续监测膀. 这项技术有助于理解膀功能和评估神经调节策略.
科学领域:
- 生物医学工程 生物医学工程
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 可穿戴技术可穿戴技术
背景情况:
- 持续的膀监测对于诊断和了解膀功能至关重要.
- 现有的方法往往是侵入性的或范围有限的.
- 神经调节策略需要有效的验证方法.
研究的目的:
- 开发和评估一种用于持续实时监测膀活动的新型植入式装置.
- 评估设备对膀功能的影响及其在正常行为过程中捕获生理数据的能力.
- 根据已确定的方法验证设备的性能.
主要方法:
- 开发了具有集成压力和阻抗传感器的意识活动泌尿学监测器 (UroMOCA).
- 无线数据传输和电池充电功能.
- 在体外校准和体内植入11只动物进行28天的监测.
主要成果:
- 在无线充电之间,UroMOCA成功连续传输数据长达44小时.
- 在体内测试证实,经过两周的愈合期,膀功能没有负面影响.
- 压力数据与参考导管有很高的相关性,体积传感器可靠地检测出空气事件.
结论:
- 乌罗莫卡 (UroMOCA) 是一种可行的工具,用于对有意识的受试者进行长期,持续的膀监测.
- 这项技术可以显著推进膀功能和神经调节的研究.
- 该设备为改善泌尿病诊断和治疗验证提供了一个有前途的方法.
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