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Updated: Jun 30, 2025

Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER
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Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER

Published on: June 23, 2012

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FASTQ和对齐阅读顺序对结构变异调用从长时间阅读测序数据的影响

Kyle J Lesack1,2, James D Wasmuth1,2

  • 1Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.

PeerJ
|March 19, 2024
PubMed
概括

从长读序列数据调用结构变体 (SV) 对FASTQ读序敏感,影响可重现性. 研究人员和工具开发人员必须考虑这种输入顺序灵敏度,以准确检测和一致的结果.

关键词:
研究的可复制性研究的可复制性.研究的稳定性研究的稳定性灵敏度分析是一种灵敏度分析.结构变化的结构变化.

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