塑料与金属支架用于具有显著固体碎片的隔墙性瘤的外壁排水:随机对照试验
Rinkal Kakadiya1, Gaurav Muktesh1, Jayanta Samanta1
1Gastroenterology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Endoscopy international open
|March 19, 2024
概括
塑料支架与金属支架同样有效地排水具有大量固体碎片的隔墙性瘤 (WON). 这项研究发现塑料支架不劣,为WON管理提供了可比的治疗选择.
科学领域:
- 胃肠病学 胃肠病学
- 干预性内镜检查是干预性的内镜检查.
- 手术瘤学手术瘤学
背景情况:
- 隔墙性亡 (WON) 管理通常涉及排水,更大的金属支架显示出对固体碎片的承诺.
- 之前的试验没有专门评估WON具有显著的固体碎片 (≥20%).
研究的目的:
- 为了比较塑料支架与金属支架的疗效,用于疏通具有显著固体碎片的症状性WON.
- 评估治疗成功,技术成功,与程序相关的结果和不良事件.
主要方法:
- 一个单中心的,开放的,非劣势性试验,涉及48名患有症状的WON和显著的固体碎片的患者.
- 患者被随机分配,接受塑料或金属支架以排水.
- 排水后3周评估结果,并对复发进行3个月的随访.
主要成果:
- 治疗成功率高且可比:金属支架的成功率为87.5%,塑料支架的成功率为83.3% (证实不劣质).
- 使用金属支架的手术时间显著缩短 (12.95分 vs 29.77分).
- 技术成功率为100%,总手术数量相似,组间不良事件没有显著差异.
结论:
- 塑料支架与金属支架相比,对于大量固体碎片的WON排水来说并没有劣势.
- 虽然金属支架提供更短的手术时间,但塑料支架提供了一个可行的替代方案.
- 建议进行更大规模的研究,以巩固这些发现并指导临床实践.
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